Ocular abnormalities in a large patient cohort with retinitis pigmentosa in Western China

Abstract Background To report the prevalence of ocular abnormalities and investigate visual acuity in a large cohort retinitis pigmentosa (RP) patients Western China. Methods The medical records ophthalmic examination reports 2127 eyes 1065 RP at one eye hospital were retrospectively reviewed to determined relationship between best corrected (BCVA) macular abnormalities. Results Nyctalopia (58.2%) blurred vision (27.1%) leading reasons for request an examination. BCVA measurements better first clinical presentation showed that 304 (28.5%) categorised as blind 220 (20.7%) low vision. most common (59.7%) cataracts (43.1%). included epiretinal membranes (51.1%), cystoid edema (18.4%), vitreomacular traction syndrome (2.4%), holes (2.3%) choroidal neovascular (0.05%). Glaucoma was found 35 (1.6%). proportions ( p = 0.001) 0.008) increased significantly with age. Cystoid associated poorer clear lens 0.002). Conclusion Cataracts are patients. Of abnormalities, may have negative effect on lens. Therefore, optical coherence tomography screening is highly recommended early detection treatment maculopathy.